Frank Y. S. Chuang
CBST Associate Director of Research and Education; Participating Guest Scientist at Lawrence Livermore National Laboratory (LLNL)
Dr. Chuang received his Bachelor
of Science degree in Bioengineering at the University of California,
Berkeley in 1987. He subsequently joined a small team of physicians
and physicists in the Division of Research Medicine and Radiation Biophysics
at Lawrence Berkeley National Laboratory to develop a new method of
treating brain tumors using high-energy particle beams. This work
was done in collaboration with neurosurgeons and neuroradiologists from
Stanford University Medical Center and the University of California,
San Francisco. With the successful completion of this program
in 1990, Frank received an NIH fellowship to join the Medical Scientist
Training Program (MSTP) at the Mount Sinai School of Medicine in New
York. Here, in the Department of Biophysics and Physiology, Frank
used advanced fluorescence microscopy and spectroscopy to investigate
the signal activation of human neutrophils in response to bacteria.
His doctoral thesis described early evidence for lipid “raft” microdomains
as a mechanism for transmembrane signaling.
In 2000, after completing his
medical training and receiving a Ph.D. in immunology and biophysics,
Dr. Chuang returned to California as a postdoctoral researcher at the
Lawrence Livermore National Laboratory – where he was the lead biomedical
scientist for several projects developing new in vitro diagnostic
systems to rapidly detect microbial pathogens in clinical samples.
This work has led to numerous publications in scientific texts and peer-reviewed
Dr. Chuang joined CBST in 2003 to support the integration of scientific research and education in biophotonics, and also to facilitate the translation of new technologies “from benchtop to bedside”. He continues to participate in research, particularly in the areas of medical nanotechnology and optical tissue imaging, as well as in broader applications of biophotonics in medicine. Dr. Chuang also works with the LLNL-UC Davis Integrated Cancer Center in the development and commercialization of a revolutionary new compact proton accelerator for medical therapy.